:: 13. August 2018
Do pancreatic beta cells facilitate their own destruction?
study led by R. Mallone has identified the molecules presented by pancreatic beta cells that mediate their abnormal recognition by the immune system and lead to their destruction in type 1 diabetes (T1D). These discoveries change...
:: 02. July 2018
Frequent monitoring of c-peptide levels
INNODIA researchers from Cambridge have developed a method to monitor what happens to the ability of type 1 diabetes patients to produce their own insulin over time, at home. They asked 32 children and adolescents with type 1 diabetes to collect a drop of blood at home on a filter paper card, also called ‘dried blood spot’, every week, in the first year from diagnosis.
:: 02. July 2018
Full day meeting at King’s College in London
Last Tuesday, around 60 nurses, clinicians and researchers from 12 different European countries gathered for a full day meeting at King’s College, London, to discuss the progress on the INNODIA clinical study. Members of the communication team, representatives of JDRF and the Patient Advisory Committee also attended the meeting.
:: 05. February 2018
We are not all type 1 diabetic, but we are all ‘auto-immune’!
In an article published on Feb, 2nd 2018 in Science Immunology, INNODIA Investigators report that the self-directed autoimmune T lymphocytes that engender the islet destruction of T1D circulate in all individuals, whether diabetic or not, but reach the pancreas only in T1D patients.
"Ariyana Salek is a 10 year old – she developed Type 1 Diabetes (T1D) at the age of 6 years old. Her brother Arman (7 years old) and mother Tracey have volunteered to join INNODIA. The volunteers give a small amount of blood to see if they have the characteristic antibodies suggesting future risk for developing T1D".
Prof. Chantal Mathieu, KU Leuven